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H5N1-Virus bleibt gefährlich
#8
Ärzte Zeitung, 29.01.2007

Das Vogelgrippe-Virus bereitet Forschern neue Sorgen

Labor-Unfall mit Hybrid-Virus aus H5N1 und humanen Grippe-Viren / Virus breitet sich in Indonesien auch unter Katzen aus

AUSTIN/SURABAYA (mut). Das Vogelgrippe-Virus hält Forscher weiter in Atem: In einem Labor in den USA kam es zu einem Unfall mit einem gentechnisch veränderten Influenza-Virus. Dabei erkrankte aber niemand. In Asien ist H5N1 auch zunehmend eine Gefahr für Katzen. Etwa 20 Prozent sind infiziert.Nach einem Protokoll, das dem Sunshine-Projekt vorliegt, einer Organisation von Biowaffen-Kritikern, kam es bereits im
April 2006 zu einem Zwischenfall in einem Labor der Universität in Austin in Texas. Dort arbeiteten Forscher an einem humanen H3N2-Influenza-Virus, welches auch Gene des hochpathogenen H5N1-Vogelgrippe-Virus enthielt. Mit solchen Hybrid-Viren soll etwa geklärt werden, ob Kreuzungen zwischen Vogelgrippe- und Humaninfluenza-Viren, wie sie auch in der Natur geschehen können, für Menschen gefährlich sind. Kritiker wie das Sunshine-Projekt werfen den Forschern jedoch vor, sie züchten Viren, die bei einem Unfall eine Pandemie auslösen können.

Der Vorfall ereignet sich, als ein Forscher die genetisch manipulierten Viren zentrifugieren wollte. Er verwendete ein falsches Zentrifugen-Röhrchen, dieses zerbrach, als die Zentrifuge lief. Statt 30 Minuten zu warten, bis sich das Viren-Aerosol in der geschlossenen Zentrifuge gesetzt hatte, öffnete er das Gerät und kontaminierte das Labor. Der Forscher hatte einen Hochsicherheits-Schutzanzug an.

Dennoch wurde er prophylaktisch mit Oseltamivir behandelt. Eine Gefährdung der Öffentlichkeit habe nicht bestanden, heißt es in dem Unfallprotokoll. Das Sunshine-Projekt sieht in dem Vorfall jedoch einen Beleg, dass die Forschung mit solchen Viren nicht sicher ist. Zu sehen ist das jetzt veröffentlichte Protokoll bei <!-- w --><a class="postlink" href="http://www.sunshine-project.org">www.sunshine-project.org</a><!-- w -->.

Ein anderes Problem zeichnet sich in Indonesien ab. In Vogelgrippe-Infektionsgebieten konnten Forscher der Universität in Surabaya bei 20 Prozent der Katzen Antikörper gegen das H5N1-Virus nachweisen. Zudem gibt es immer wieder Berichte über ein Katzensterben, teilt das Magazin "New Scientist" in seiner Online-Ausgabe mit.

Befürchtet wird, dass sich das Virus über eine Verbreitung bei Katzen an Säugetiere anpasst und somit neue Stämme bildet, die auch auf Menschen übertragbar sind. Noch infizieren sich Katzen jedoch kaum untereinander, sondern indem sie kranke oder tote Vögel fressen.


Copyright © 1997-2007 by Ärzte Zeitung


Gruß
Drui


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H5N1-Virus bleibt gefährlich - von Druidelix - 19.09.2006, 08:13
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Vogelgrippe Virus bereitet Forscher neue Sorgen - von Druidelix - 29.01.2007, 14:33
[Kein Betreff] - von Druidelix - 08.02.2007, 14:43

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